How many U.S. Senators serve in the Senate?

The correct answer is one hundred (100) because the United States Senate is composed of exactly two senators from each of the 50 states, regardless of the state's population. This structure is established by the U.S. Constitution, specifically in Article I, Section 3. Therefore, with 50 states each represented by two senators, the total number of U.S. Senators is 100. This design aims to ensure equal representation for each state in the legislative process, helping to balance the interests of smaller states with those of larger states. The other options do not reflect this composition and are incorrect as they suggest either an inflated or diminished number of senators.